a-researcher-resolves-a-mixture-of-peptides-using-isoelectric-focusing The intricate world of molecular biology hinges on the precise translation of genetic information into functional proteins. A fundamental step in this process is understanding how a specific peptide sequence, such as NH2-Phe-Pro-Lys-Gly-Phe-Pro-COOH, is encoded within the DNA. This particular sequence features six amino acids, beginning with Phe (phenylalanine) and ending with Pro (proline). Among these are Pro (proline), Lys (lysine), and Gly (glycine) – each playing a unique role in the final peptide's structure and function.2018年12月4日—A peptide has the sequenceNH2-phe-pro-lys-gly-phe-pro-COOH. What is the sequence in DNA that codes for this peptide? Select one: a. 3' AUG-AAA- ... The presence of a free NH2 group at one terminus and a COOH group at the other signifies the characteristic termini of a polypeptide chain.
To decipher the genetic code behind this peptide, we must first consider the mRNA sequence that would directly translate into these amino acids. The genetic code is degenerate, meaning that multiple mRNA codons can specify the same amino acid. However, for a given peptide sequence, there is a corresponding mRNA sequence. For the NH2-Phe-Pro-Lys-Gly-Phe-Pro-COOH chain, the mRNA codons are as follows:
* Phe: UUU or UUC
* Pro: CCU, CCC, CCA, or CCG
* Lys: AAA or AAG
* Gly: GGU, GGC, GGA, or GGG
Given the typical representation in molecular biology problems, the mRNA sequence for NH2-phe-pro-lys-gly-phe-pro-COOH is derived from a set of commonly used codons. Following the order of the amino acids, a possible mRNA sequence is 5'-UUU-CCC-AAA-GGG-UUU-CCC-3'. This mRNA sequence is crucial because it's directly complementary to the template DNA strand and nearly identical to the coding DNA strand (with uracil replaced by thymine).Amino Acids, Peptides, and Proteins
The coding strand of the DNA, often referred to as the sense strand, will have a base sequence that is complementary to the mRNA, with the exception that thymine (T) replaces uracil (U).作者:MO Olson·1976·被引用次数:83—TheCOOH-terminal amino acidsequenceis the same as that of histone 2A, naely: -His-His-Lys-Ala-Lys-Gly-Lys-COOH. Publication types. Therefore, to determine the DNA sequence that codes for NH2-Phe-Pro-Lys-Gly-Phe-Pro-COOH, we can use the derived mRNA sequence and substitute T for U.A peptide has the sequenceNH2-phe-pro-lys-gly-phe-pro-COOH. Which of the following sequences in the coding strand of the DNA could code for this peptide?
Each amino acid in the peptide sequence corresponds to a specific triplet of bases, a codon. Let's break down the coding strand DNA sequence based on the mRNA sequence:
* Phe (from UUU) translates to TTT in the coding DNA strandA peptide has the sequenceNH2-phe-pro-lys-gly-phe-pro- COOH. Which of the following sequences in the coding strand of the DNA could code for this. Show ....
* Pro (from CCC) translates to CCC in the coding DNA strand.
* Lys (from AAA) translates to AAA in the coding DNA strandAnswered: A peptide has the sequence ....
* Gly (from GGG) translates to GGG in the coding DNA strand.
* Phe (from UUU) translates to TTT in the coding DNA strand.
* Pro (from CCC) translates to CCC in the coding DNA strand.
Thus, a potential coding strand DNA sequence that could code for the peptide NH2-Phe-Pro-Lys-Gly-Phe-Pro-COOH is 5'-TTT-CCC-AAA-GGG-TTT-CCC-3'.GenScript offers a variety of peptide synthesis services with both natural and non-standard/unnatural amino acids. It's important to note that due to the degeneracy of the genetic code, other DNA sequences could also code for this same peptide by using alternative codons for Phe, Pro, Lys, and Gly.All About Amino Acids - JPT Peptide Technologies For instance, if the mRNA used UUC for Phe, the DNA coding strand would have TTC. However, the provided sequence NH2-phe-pro-lys-gly-phe-pro-COOH is directly linked to these specific codons and their DNA counterpartsLecture 18 Post-Class Questions Flashcards.
The process of transcription and translation represents a fundamental aspect of molecular biology, as detailed in resources discussing the information in DNA determining cellular function. Understanding these relationships is vital for fields ranging from genetic research to the development of novel peptide therapeutics. The ability to predict DNA sequences from peptide sequences, and vice versa, is a cornerstone of modern biotechnology and scientific inquiry. This meticulous transfer of genetic information from DNA to RNA and finally to proteins, exemplified by the NH2-Phe-Pro-Lys-Gly-Phe-Pro-COOH example, underscores the elegant complexity of life at the molecular level[FREE] A peptide has the sequence NH_2-phe-pro-lys-gly- .... The study of amino acids, their properties, and their arrangement into peptides and proteins is an ongoing area of scientific exploration, with researchers continually uncovering new insights into their roles and applications. Variations in peptide sequence, like those seen in NH2- and COOH-terminal sequence of nuclear portein A24, highlight the diversity and specificity of biological molecules[FREE] A peptide has the sequence NH_2-phe-pro-lys-gly- ....
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